Publication Highlights

Epidemiology

Diabetes in China: a societal solution for a personal challenge.

Chan JC, Zhang Y, Ning G.

Lancet Diabetes Endocrinol. 2014 Dec;2(12):969-79. doi: 10.1016/S2213-8587(14)70144-5. Epub

Causes of type 2 diabetes in China.

Ma RC, Lin X, Jia W.

Lancet Diabetes Endocrinol. 2014 Dec;2(12):980-91. doi: 10.1016/S2213-8587(14)70145-7. Epub

Diabetes and its comorbidities–where East meets West.

Kong AP, Xu G, Brown N, So WY, Ma RC, Chan JC.

Nat Rev Endocrinol. 2013 Sep;9(9):537-47. doi: 10.1038/nrendo.2013.102. Epub 2013 May 28. Review.       

Diabetes in Asia: epidemiology, risk factors, and pathophysiology.

Chan JC, Malik V, Jia W, Kadowaki T, Yajnik CS, Yoon KH, Hu FB.

JAMA. 2009 May 27;301(20):2129-40. doi: 10.1001/jama.2009.726. Review.

Diabetes in Asia.

Ramachandran A, Ma RC, Snehalatha C.

Lancet. 2010 Jan 30;375(9712):408-18. doi: 10.1016/S0140-6736(09)60937-5. Epub 2009 Oct 28.

Disease Management

Effects of telephone-based peer support in patients with type 2 diabetes mellitus receiving integrated care: a randomized clinical trial.

Chan JC, Sui Y, Oldenburg B, Zhang Y, Chung HH, Goggins W, Au S, Brown N, Ozaki R, Wong RY, Ko GT, Fisher E; JADE and PEARL Project Team.

JAMA Intern Med. 2014 Jun;174(6):972-81. doi: 10.1001/jamainternmed.2014.655.

Effects of structured versus usual care on renal endpoint in type 2 diabetes: the SURE study: a randomized multicenter translational study.

Chan JC, So WY, Yeung CY, Ko GT, Lau IT, Tsang MW, Lau KP, Siu SC, Li JK, Yeung VT, Leung WY, Tong PC; SURE Study Group.

Diabetes Care. 2009 Jun;32(6):977-82. doi: 10.2337/dc08-1908.

Effectiveness of telephone counselling by a pharmacist in reducing mortality in patients receiving polypharmacy: randomised controlled trial.

Wu JY, Leung WY, Chang S, Lee B, Zee B, Tong PC, Chan JC.

BMJ. 2006 Sep 9;333(7567):522. Epub 2006 Aug 17.

Effects of structured care by a pharmacist-diabetes specialist team in patients with type 2 diabetic nephropathy.

Leung WY, So WY, Tong PC, Chan NN, Chan JC.

Am J Med. 2005 Dec;118(12):1414.

Effects of protocol-driven care versus usual outpatient clinic care on survival rates in patients with type 2 diabetes.

So WY, Tong PC, Ko GT, Leung WY, Chow CC, Yeung VT, Chan WB, Critchley JA, Cockram CS, Chan JC.

Am J Manag Care. 2003 Sep;9(9):606-15.

Young-onset Diabetes

Premature mortality and comorbidities in young-onset diabetes: a 7-year prospective analysis.

Chan JC, Lau ES, Luk AO, Cheung KK, Kong AP, Yu LW, Choi KC, Chow FC, Ozaki R, Brown N, Yang X, Bennett PH, Ma RC, So WY.

Am J Med. 2014 Jul;127(7):616-24. doi: 10.1016/j.amjmed.2014.03.018. Epub 2014 Mar 25.

Prospective study on the incidences of cardiovascular-renal complications in Chinese patients with young-onset type 1 and type 2 diabetes.

Luk AO, Lau ES, So WY, Ma RC, Kong AP, Ozaki R, Chow FC, Chan JC.

Diabetes Care. 2014;37(1):149-57. doi: 10.2337/dc13-1336.

Metabolic profiles and treatment gaps in young-onset type 2 diabetes in Asia (the JADE programme): a cross-sectional study of a prospective cohort.

Yeung RO, Zhang Y, Luk A, Yang W, Sobrepena L, Yoon KH, Aravind SR, Sheu W, Nguyen TK, Ozaki R, Deerochanawong C, Tsang CC, Chan WB, Hong EG, Do TQ, Cheung Y, Brown N, Goh SY, Ma RC, Mukhopadhyay M, Ojha AK, Chakraborty S, Kong AP, Lau W, Jia W, Li W, Guo X, Bian R, Weng J, Ji L, Reyes-dela Rosa M, Toledo RM, Himathongkam T, Yoo SJ, Chow CC, Ho LL, Chuang LM, Tutino G, Tong PC, So WY, Wolthers T, Ko G, Lyubomirsky G, Chan JC.

Lancet Diabetes Endocrinol. 2014 Dec;2(12):935-43. doi: 10.1016/S2213-8587(14)70137-8. Epub

Phenotypic and genetic clustering of diabetes and metabolic syndrome in Chinese families with type 2 diabetes mellitus.

Li JK, Ng MC, So WY, Chiu CK, Ozaki R, Tong PC, Cockram CS, Chan JC.

Diabetes Metab Res Rev. 2006 Jan-Feb;22(1):46-52.

Familial early-onset type 2 diabetes in Chinese patients: obesity and genetics have more significant roles than autoimmunity.

Ng MC, Lee SC, Ko GT, Li JK, So WY, Hashim Y, Barnett AH, Mackay IR, Critchley JA, Cockram CS, Chan JC.

Diabetes Care. 2001 Apr;24(4):663-71.

 

Genome and Genetics of Diabetes    

Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation.

Lou S, Lee HM, Qin H, Li JW, Gao Z, Liu X, Chan LL, Kl Lam V, So WY, Wang Y, Lok S, Wang J, Ma RC, Tsui SK, Chan JC, Chan TF, Yip KY.

Genome Biol. 2014 Jul 30;15(7):408. doi: 10.1186/s13059-014-0408-0.

Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4.

Ma RC, Hu C, Tam CH, Zhang R, Kwan P, Leung TF, Thomas GN, Go MJ, Hara K, Sim X, Ho JS, Wang C, Li H, Lu L, Wang Y, Li JW, Wang Y, Lam VK, Wang J, Yu W, Kim YJ, Ng DP, Fujita H, Panoutsopoulou K, Day-Williams AG, Lee HM, Ng AC, Fang YJ, Kong AP, Jiang F, Ma X, Hou X, Tang S, Lu J, Yamauchi T, Tsui SK, Woo J, Leung PC, Zhang X, Tang NL, Sy HY, Liu J, Wong TY, Lee JY, Maeda S, Xu G, Cherny SS, Chan TF, Ng MC, Xiang K, Morris AP; DIAGRAM Consortium, Keildson S; MuTHER Consortium, Hu R, Ji L, Lin X, Cho YS, Kadowaki T, Tai ES, Zeggini E, McCarthy MI, Hon KL, Baum L, Tomlinson B, So WY, Bao Y, Chan JC, Jia W.

Diabetologia. 2013 Jun;56(6):1291-305. doi: 10.1007/s00125-013-2874-4. Epub 2013 Mar 27.

Genetic associations of type 2 diabetes with islet amyloid polypeptide processing and degrading pathways in asian populations.

Lam VK, Ma RC, Lee HM, Hu C, Park KS, Furuta H, Wang Y, Tam CH, Sim X, Ng DP, Liu J, Wong TY, Tai ES, Morris AP; DIAGRAM Consortium, Tang NL, Woo J, Leung PC, Kong AP, Ozaki R, Jia WP, Lee HK, Nanjo K, Xu G, Ng MC, So WY, Chan JC.

PLoS One. 2013 Jun 11;8(6):e62378. doi: 10.1371/journal.pone.0062378. Print 2013.

Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese.

Ma RC, Lee HM, Lam VK, Tam CH, Ho JS, Zhao HL, Guan J, Kong AP, Lau E, Zhang G, Luk A, Wang Y, Tsui SK, Chan TF, Hu C, Jia WP, Park KS, Lee HK, Furuta H, Nanjo K, Tai ES, Ng DP, Tang NL, Woo J, Leung PC, Xue H, Wong J, Leung PS, Lau TC, Tong PC, Xu G, Ng MC, So WY, Chan JC.

PLoS One. 2014 Jan 20;9(1):e84770. doi: 10.1371/journal.pone.0084770. eCollection 2014.

Genome-wide scan for type 2 diabetes loci in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25.

Ng MC, So WY, Cox NJ, Lam VK, Cockram CS, Critchley JA, Bell GI, Chan JC.

Diabetes. 2004 Jun;53(6):1609-13.

 

Genetics of Diabetic Complications

Genetic variants of the protein kinase C-beta 1 gene and development of end-stage renal disease in patients with type 2 diabetes.

Ma RC, Tam CH, Wang Y, Luk AO, Hu C, Yang X, Lam V, Chan AW, Ho JS, Chow CC, Tong PC, Jia W, Ng MC, So WY, Chan JC.

JAMA. 2010 Aug 25;304(8):881-9. doi: 10.1001/jama.2010.1191.

Prognostic effect of insertion/deletion polymorphism of the ace gene on renal and cardiovascular clinical outcomes in Chinese patients with type 2 diabetes.

Wang Y, Ng MC, So WY, Tong PC, Ma RC, Chow CC, Cockram CS, Chan JC.

Diabetes Care. 2005 Feb;28(2):348-54.

Phenotype-genotype interactions on renal function in type 2 diabetes: an analysis using structural equation modelling.

Song XY, Lee SY, Ma RC, So WY, Cai JH, Tam C, Lam V, Ying W, Ng MC, Chan JC.

Diabetologia. 2009 Aug;52(8):1543-53. doi: 10.1007/s00125-009-1400-1. Epub 2009 May 29.

Aldose reductase genotypes and cardiorenal complications: an 8-year prospective analysis of 1,074 type 2 diabetic patients.

So WY, Wang Y, Ng MC, Yang X, Ma RC, Lam V, Kong AP, Tong PC, Chan JC.

Diabetes Care. 2008 Nov;31(11):2148-53. doi: 10.2337/dc08-0712. Epub 2008 Aug 20.

Effect of hepatic lipase -514C->T polymorphism and its interactions with apolipoprotein C3 -482C->T and apolipoprotein E exon 4 polymorphisms on the risk of nephropathy in chinese type 2 diabetic patients.

Baum L, Ng MC, So WY, Lam VK, Wang Y, Poon E, Tomlinson B, Cheng S, Lindpaintner K, Chan JC.

Diabetes Care. 2005 Jul;28(7):1704-9.

Depression and Psychological Health

Effects of Providing Peer Support on Diabetes Management in People With Type 2 Diabetes.

Yin J, Wong R, Au S, Chung H, Lau M, Lin L, Tsang C, Lau K, Ozaki R, So W, Ko G, Luk A, Yeung R, Chan JC.

Ann Fam Med. 2015 Aug;13 Suppl 1:S42-9. doi: 10.1370/afm.1853.

Depression in Chinese patients with type 2 diabetes: associations with hyperglycemia, hypoglycemia, and poor treatment adherence.

Zhang Y, Ting RZ, Yang W, Jia W, Li W, Ji L, Guo X, Kong AP, Wing YK, Luk AO, Sartorius N, Morisky DE, Oldenburg B, Weng J, Chan JC; China Depression in Chinese Patients with Type 2 Diabetes (DD2) Study Group.

J Diabetes. 2014 Oct 28. doi: 10.1111/1753-0407.12238. [Epub ahead of print]

Measuring depressive symptoms using the Patient Health Questionnaire-9 in Hong Kong Chinese subjects with type 2 diabetes.

Zhang Y, Ting R, Lam M, Lam J, Nan H, Yeung R, Yang W, Ji L, Weng J, Wing YK, Sartorius N, Chan JC.

J Affect Disord. 2013 Nov;151(2):660-6. doi: 10.1016/j.jad.2013.07.014. Epub 2013 Jul 31.

Co-occurrence of diabetes and depression: conceptual considerations for an emerging global health challenge.

Fisher EB, Chan JC, Nan H, Sartorius N, Oldenburg B.

J Affect Disord. 2012 Oct;142 Suppl:S56-66. doi: 10.1016/S0165-0327(12)70009-5. Review.

Diabetes-related distress and physical and psychological health in chinese type 2 diabetic patients.

Ting RZ, Nan H, Yu MW, Kong AP, Ma RC, Wong RY, Loo K, So WY, Chow CC, Ko GT, Wing YK, Chan JC.

Diabetes Care. 2011 May;34(5):1094-6. doi: 10.2337/dc10-1612. Epub 2011 Mar 11.

 

Cardiovascular-renal Complications

A new tool to detect kidney disease in Chinese type 2 diabetes patients: comparison of EZSCAN with standard screening methods.

Ozaki R, Cheung KK, Wu E, Kong A, Yang X, Lau E, Brunswick P, Calvet JH, Deslypere JP, Chan JC.

Diabetes Technol Ther. 2011 Sep;13(9):937-43. doi: 10.1089/dia.2011.0023. Epub 2011 Jun 29.

Erectile dysfunction predicts coronary heart disease in type 2 diabetes.

Ma RC, So WY, Yang X, Yu LW, Kong AP, Ko GT, Chow CC, Cockram CS, Chan JC, Tong PC.

J Am Coll Cardiol. 2008 May 27;51(21):2045-50. doi: 10.1016/j.jacc.2008.02.051.

Metabolic syndrome predicts new onset of chronic kidney disease in 5,829 patients with type 2 diabetes: a 5-year prospective analysis of the Hong Kong Diabetes Registry.

Luk AO, So WY, Ma RC, Kong AP, Ozaki R, Ng VS, Yu LW, Lau WW, Yang X, Chow FC, Chan JC, Tong PC; Hong Kong Diabetes Registry.

Diabetes Care. 2008 Dec;31(12):2357-61. doi: 10.2337/dc08-0971. Epub 2008 Oct 3.

Effects of treatment targets on subsequent cardiovascular events in Chinese patients with type 2 diabetes.

Kong AP, Yang X, Ko GT, So WY, Chan WB, Ma RC, Ng VW, Chow CC, Cockram CS, Tong PC, Wong V, Chan JC.

Diabetes Care. 2007 Apr;30(4):953-9. Epub 2007 Jan 26.

Glomerular filtration rate, cardiorenal end points, and all-cause mortality in type 2 diabetic patients.

So WY, Kong AP, Ma RC, Ozaki R, Szeto CC, Chan NN, Ng V, Ho CS, Lam CW, Chow CC, Cockram CS, Chan JC, Tong PC.

Diabetes Care. 2006 Sep;29(9):2046-52.

 

Clinical Trials

Effect of Finerenone on Albuminuria in Patients With Diabetic Nephropathy: A Randomized Clinical Trial.

Bakris GL, Agarwal R, Chan JC, Cooper ME, Gansevoort RT, Haller H, Remuzzi G, Rossing P, Schmieder RE, Nowack C, Kolkhof P, Joseph A, Pieper A, Kimmeskamp-Kirschbaum N, Ruilope LM; Mineralocorticoid Receptor Antagonist Tolerability Study–Diabetic Nephropathy (ARTS-DN) Study Group.

JAMA. 2015 Sep 1;314(9):884-94. doi: 10.1001/jama.2015.10081.

Insulin glargine versus sitagliptin in insulin-naive patients with type 2 diabetes mellitus uncontrolled on metformin (EASIE): a multicentre, randomised open-label trial.

Aschner P, Chan J, Owens DR, Picard S, Wang E, Dain MP, Pilorget V, Echtay A, Fonseca V; EASIE investigators.

Lancet. 2012 Jun 16;379(9833):2262-9. doi: 10.1016/S0140-6736(12)60439-5. Epub 2012 Jun 9.

Effects of olmesartan on renal and cardiovascular outcomes in type 2 diabetes with overt nephropathy: a multicentre, randomised, placebo-controlled study.

Imai E, Chan JC, Ito S, Yamasaki T, Kobayashi F, Haneda M, Makino H; ORIENT study investigators.

Diabetologia. 2011 Dec;54(12):2978-86. doi: 10.1007/s00125-011-2325-z. Epub 2011 Oct 13.

Renin angiotensin aldosterone system blockade and renal disease in patients with type 2 diabetes. An Asian perspective from the RENAAL Study.

Chan JC, Wat NM, So WY, Lam KS, Chua CT, Wong KS, Morad Z, Dickson TZ, Hille D, Zhang Z, Cooper ME, Shahinfar S, Brenner BM, Kurokawa K; Asian RENAAL Study Investigators.

Diabetes Care. 2004 Apr;27(4):874-9.

Comparison of insulin with or without continuation of oral hypoglycemic agents in the treatment of secondary failure in NIDDM patients.

Chow CC, Tsang LW, Sorensen JP, Cockram CS.

Diabetes Care. 1995 Mar;18(3):307-14.

 

 

Diabetes and Cancer

Drug-subphenotype interactions for cancer in type 2 diabetes mellitus.

Yang X, Lee HM, Chan JC.

Nat Rev Endocrinol. 2015 Jun;11(6):372-9. doi: 10.1038/nrendo.2015.37. Epub 2015 Mar 24.

                   

Additive effects of blood glucose lowering drugs, statins and renin-angiotensin system blockers on all-site cancer risk in patients with type 2 diabetes.

Kong AP, Yang X, So WY, Luk A, Ma RC, Ozaki R, Cheung KK, Lee HM, Yu L, Xu G, Chow CC, Chan JC.

BMC Med. 2014 May 13;12:76. doi: 10.1186/1741-7015-12-76.

 

Severe hypoglycemia identifies vulnerable patients with type 2 diabetes at risk for premature death and all-site cancer: the Hong Kong diabetes registry.

Kong AP, Yang X, Luk A, Ma RC, So WY, Ozaki R, Ting R, Cheung K, Ho CS, Chan MH, Chow CC, Chan JC.

Diabetes Care. 2014 Apr;37(4):1024-31. doi: 10.2337/dc13-2507. Epub 2014 Feb 10.

 

Associations of hyperglycemia and insulin usage with the risk of cancer in type 2 diabetes: the Hong Kong diabetes registry.

Yang X, Ko GT, So WY, Ma RC, Yu LW, Kong AP, Zhao H, Chow CC, Tong PC, Chan JC.

Diabetes. 2010 May;59(5):1254-60. doi: 10.2337/db09-1371. Epub 2010 Feb 25.

 

Additive interaction between the renin-angiotensin system and lipid metabolism for cancer in type 2 diabetes.

Yang X, Zhao H, Sui Y, Ma RC, So WY, Ko GT, Kong AP, Ozaki R, Yeung CY, Xu G, Tong PC, Chan JC.

Diabetes. 2009 Jul;58(7):1518-25. doi: 10.2337/db09-0105. Epub 2009 Apr 28.

Joint Asia Diabetes Evaluation Program

Delivery of integrated diabetes care using logistics and information technology–the Joint Asia Diabetes Evaluation (JADE) program.

Chan JC, Ozaki R, Luk A, Kong AP, Ma RC, Chow FC, Wong P, Wong R, Chung H, Chiu C, Wolthers T, Tong PC, Ko GT, So WY, Lyubomirsky G; JADE Collaborative Study Group.

Diabetes Res Clin Pract. 2014 Dec;106 Suppl 2:S295-304. doi: 10.1016/S0168-8227(14)70733-8.

Borderline ankle-brachial index is associated with increased prevalence of micro- and macrovascular complications in type 2 diabetes: A cross-sectional analysis of 12,772 patients from the Joint Asia Diabetes Evaluation Program.

Yan BP, Zhang Y, Kong AP, Luk AO, Ozaki R, Yeung R, Tong PC, Chan WB, Tsang CC, Lau KP, Cheung Y, Wolthers T, Lyubomirsky G, So WY, Ma RC, Chow FC, Chan JC; Hong Kong JADE Study Group.

Diab Vasc Dis Res. 2015 Sep;12(5):334-41. doi: 10.1177/1479164115590559. Epub 2015 Jul 3.

Gender, diabetes education, and psychosocial factors are associated with persistent poor glycemic control in patients with type 2 diabetes in the Joint Asia Diabetes Evaluation (JADE) program.

Yin J, Yeung R, Luk A, Tutino G, Zhang Y, Kong A, Chung H, Wong R, Ozaki R, Ma R, Tsang CC, Tong P, So W, Chan J.

J Diabetes. 2015 Jan 7. doi: 10.1111/1753-0407.12262. [Epub ahead of print]

From design to implementation–the Joint Asia Diabetes Evaluation (JADE) program: a descriptive report of an electronic web-based diabetes management program.

Ko GT, So WY, Tong PC, Le Coguiec F, Kerr D, Lyubomirsky G, Tamesis B, Wolthers T, Nan J, Chan J.

BMC Med Inform Decis Mak. 2010 May 13;10:26. doi: 10.1186/1472-6947-10-26.

The Joint Asia Diabetes Evaluation (JADE) Program: a web-based program to translate evidence to clinical practice in Type 2 diabetes.

Chan J, So W, Ko G, Tong P, Yang X, Ma R, Kong A, Wong R, Le Coguiec F, Tamesis B, Wolthers T, Lyubomirsky G, Chow P.

Diabet Med. 2009 Jul;26(7):693-9. doi: 10.1111/j.1464-5491.2009.02751.x.

Gestational Diabetes, Maternal Health and Fetal Origin

Maternal diabetes, gestational diabetes and the role of epigenetics in their long term effects on offspring.

Ma RC, Tutino GE, Lillycrop KA, Hanson MA, Tam WH.

Prog Biophys Mol Biol. 2015 Jul;118(1-2):55-68. doi: 10.1016/j.pbiomolbio.2015.02.010. Epub 2015 Mar 16. Review.

 

Maternal history of diabetes is associated with increased cardiometabolic risk in Chinese.

Tam CH, Wang Y, Luan J, Lee HM, Luk AO, Tutino GE, Tong PC, Kong AP, So WY, Chan JC, Ma RC.

Nutr Diabetes. 2014 Mar 10;4:e112. doi: 10.1038/nutd.2014.9.

 

Diabetes and pregnancy: perspectives from Asia.

Tutino GE, Tam WH, Yang X, Chan JC, Lao TT, Ma RC.

Diabet Med. 2014 Mar;31(3):302-18. doi: 10.1111/dme.12396. Review.

 

Non-linear relationship between birthweight and cardiometabolic risk factors in Chinese adolescents and adults.

Tam CH, Wang Y, Luan J, Lee HM, Luk AO, Tutino GE, Tong PC, Ko GT, Ozaki R, Tam WH, Kong AP, So WY, Chan JC, Ma RC.

Diabet Med. 2015 Feb;32(2):220-5. doi: 10.1111/dme.12630. Epub 2014 Nov 30.

 

Gestational diabetes, maternal obesity, and the NCD burden.

Ma RC, Chan JC, Tam WH, Hanson MA, Gluckman PD.

Clin Obstet Gynecol. 2013 Sep;56(3):633-41. doi: 10.1097/GRF.0b013e31829e5bb0. Review.

Childhood Obesity and Cardiometabolic Health

A randomized controlled trial to investigate the impact of a low glycemic index (GI) diet on body mass index in obese adolescents.

Kong AP, Choi KC, Chan RS, Lok K, Ozaki R, Li AM, Ho CS, Chan MH, Sea M, Henry CJ, Chan JC, Woo J.

BMC Public Health. 2014 Feb 19;14:180. doi: 10.1186/1471-2458-14-180.

 

Association between sleep architecture and glucose tolerance in children and adolescents.

Zhu Y, Li AM, Au CT, Kong AP, Zhang J, Wong CK, Chan JC, Wing YK.

J Diabetes. 2015 Jan;7(1):10-5.

 

Associations of uric acid and gamma-glutamyltransferase (GGT) with obesity and components of metabolic syndrome in children and adolescents.

Kong AP, Choi KC, Ho CS, Chan MH, Ozaki R, Chan CW, Chan JC.

Pediatr Obes. 2013 Oct;8(5):351-7. doi: 10.1111/j.2047-6310.2012.00115.x. Epub 2012 Dec 13.

 

Serum concentrations of insulin-like growth factor-I, insulin-like growth factor binding protein-3 and cardiovascular risk factors in adolescents.

Kong AP, Choi KC, Wong GW, Ko GT, Ho CS, Chan MH, Ozaki R, Ma RC, Lau JT, Chan JC.

Ann Clin Biochem. 2011 May;48(Pt 3):263-9. doi: 10.1258/acb.2011.010267. Epub 2011 Apr 8.

 

Overweight, family history of diabetes and attending schools of lower academic grading are independent predictors for metabolic syndrome in Hong Kong Chinese adolescents.

Ozaki R, Qiao Q, Wong GW, Chan MH, So WY, Tong PC, Ho CS, Ko GT, Kong AP, Lam CW, Tuomilehto J, Chan JC.

Arch Dis Child. 2007 Mar;92(3):224-8. Epub 2006 Nov 6.

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